Ezetimibe +
Simvastatin Tablets

Project Image
Thumb Image
Thumb Image
Thumb Image
Thumb Image

Therapeutic Indication

Primary hypercholesterolemia
Mixed dyslipidemia
Reduction of LDL cholesterol
Adjunct to statin therapy
Prevention of cardiovascular risk
+91 85919 78885

Ezetimibe + Simvastatin

Tablet

Ezetimibe and Simvastatin combination tablet is a lipid-lowering medication used to reduce elevated cholesterol levels. It works by decreasing cholesterol absorption from the intestine and reducing cholesterol synthesis in the liver, thereby effectively lowering LDL (bad cholesterol) and improving overall lipid profile.

Speciality Dual Action | Lipid Control
Tags Cholesterol | Statin | Lipid
Strength
  • Ezetimibe 10 mg
  • Simvastatin 10/20 mg
Packing Size
  • 10 Tablets

Check all Tablets Range

Click to know More

Mechanism

  • Ezetimibe inhibits cholesterol absorption at the intestinal brush border via NPC1L1 transporter.
  • Simvastatin inhibits HMG-CoA reductase, reducing cholesterol synthesis in the liver.
  • Combined action leads to significant reduction in LDL and total cholesterol.

Side Effects

  • Headache
  • Muscle pain (myalgia)
  • Abdominal pain
  • Fatigue
  • Elevated liver enzymes

Contraindication

  • Active liver disease
  • Pregnancy & lactation
  • Hypersensitivity to components

Interaction

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, erythromycin)
  • Cyclosporine
  • Fibrates (especially gemfibrozil)
  • Warfarin

Warning and Precautions

  • Monitor liver function regularly.
  • Use cautiously in patients with liver disease.
  • Risk of myopathy/rhabdomyolysis.
  • Avoid alcohol consumption.
  • Not recommended during pregnancy or breastfeeding; use only if benefit outweighs risk under medical supervision.

Dosage

As directed by the Physician.

Disclaimer

All product details on this website are for reference and informational purposes only and are not directed at patients or consumers.
As a contract manufacturer, DM Pharma Pvt Ltd is not responsible for the marketing or end use of these products and disclaims all liability arising from reliance on this information.
Please consult a healthcare professional before using any medicinal product.